Obesity and endoplasmic Reticulum (ER) stresses

Obesity and endoplasmic Reticulum (ER) stresses

In obesity, the adipose cells behave as inflammatory source and result to low grade inflammation. This systemic inflammation along with oxidative stress is a silent killer and damages other vital organs also. High metabolic process, induced due to high nutritional intake, results to endoplasmic reti...

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Bibliographic Details
Main Authors: Yamini Bhushan Tripathi, Vivek ePandey
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
Inflammation
Obesity
metabolic syndrome
er stress
Inflammation.
Mitochondrial stress
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00240/full
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spelling doaj-5e7b7c576437490b987f9b7665b19bc52020-11-24T23:06:24ZengFrontiers Media S.A.Frontiers in Immunology1664-32242012-08-01310.3389/fimmu.2012.0024025990Obesity and endoplasmic Reticulum (ER) stressesYamini Bhushan Tripathi0Vivek ePandey1Banaras Hindu UniversityBanaras Hindu UniversityIn obesity, the adipose cells behave as inflammatory source and result to low grade inflammation. This systemic inflammation along with oxidative stress is a silent killer and damages other vital organs also. High metabolic process, induced due to high nutritional intake, results to endoplasmic reticulum (ER) stress and mitochondrial stress. This review describes the triggering factor and basic mechanism behind the obesity mediated these stresses in relation to inflammation. Efforts have been made to describe the effect- response cycle between adipocytes and non-adipocyte cells with reference to metabolic syndrome.http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00240/fullInflammationObesitymetabolic syndromeer stressInflammation.Mitochondrial stress
collection DOAJ
language English
format Article
sources DOAJ
author Yamini Bhushan Tripathi
Vivek ePandey
spellingShingle Yamini Bhushan Tripathi
Vivek ePandey
Obesity and endoplasmic Reticulum (ER) stresses
Frontiers in Immunology
Inflammation
Obesity
metabolic syndrome
er stress
Inflammation.
Mitochondrial stress
author_facet Yamini Bhushan Tripathi
Vivek ePandey
author_sort Yamini Bhushan Tripathi
title Obesity and endoplasmic Reticulum (ER) stresses
title_short Obesity and endoplasmic Reticulum (ER) stresses
title_full Obesity and endoplasmic Reticulum (ER) stresses
title_fullStr Obesity and endoplasmic Reticulum (ER) stresses
title_full_unstemmed Obesity and endoplasmic Reticulum (ER) stresses
title_sort obesity and endoplasmic reticulum (er) stresses
publisher Frontiers Media S.A.
series Frontiers in Immunology
issn 1664-3224
publishDate 2012-08-01
description In obesity, the adipose cells behave as inflammatory source and result to low grade inflammation. This systemic inflammation along with oxidative stress is a silent killer and damages other vital organs also. High metabolic process, induced due to high nutritional intake, results to endoplasmic reticulum (ER) stress and mitochondrial stress. This review describes the triggering factor and basic mechanism behind the obesity mediated these stresses in relation to inflammation. Efforts have been made to describe the effect- response cycle between adipocytes and non-adipocyte cells with reference to metabolic syndrome.
topic Inflammation
Obesity
metabolic syndrome
er stress
Inflammation.
Mitochondrial stress
url http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00240/full
work_keys_str_mv AT yaminibhushantripathi obesityandendoplasmicreticulumerstresses
AT vivekepandey obesityandendoplasmicreticulumerstresses
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