CB2 Receptor Stimulation and Dexamethasone Restore the Anti-Inflammatory and Immune-Regulatory Properties of Mesenchymal Stromal Cells of Children with Immune Thrombocytopenia

CB2 Receptor Stimulation and Dexamethasone Restore the Anti-Inflammatory and Immune-Regulatory Properties of Mesenchymal Stromal Cells of Children with Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by antibody-mediated platelet destruction, with a complex and unclear pathogenesis. The impaired immunosuppressive capacity of mesenchymal stromal cells in ITP patients (ITP-MSCs) might play a role in the development of the diseas...

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Bibliographic Details
Main Authors: Francesca Rossi, Chiara Tortora, Giuseppe Palumbo, Francesca Punzo, Maura Argenziano, Maddalena Casale, Alessandra Di Paola, Franco Locatelli, Silverio Perrotta
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
immune thrombocytopenia
mesenchymal stromal cells
cannabinoid receptor 2
dexamethasone
Online Access:https://www.mdpi.com/1422-0067/20/5/1049

Internet

https://www.mdpi.com/1422-0067/20/5/1049

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