Bazedoxifene, a GP130 Inhibitor, Modulates EMT Signaling and Exhibits Antitumor Effects in HPV-Positive Cervical Cancer

Bazedoxifene, a GP130 Inhibitor, Modulates EMT Signaling and Exhibits Antitumor Effects in HPV-Positive Cervical Cancer

Persistent HPV (Human Papillomavirus) infection is the primary cause of cervical cancer. Despite the development of the HPV vaccine to prevent infections, cervical cancer is still a fatal malignant tumor and metastatic disease, and it is often difficult to treat, so a new treatment strategy is neede...

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Bibliographic Details
Main Authors: Leekyung Kim, Sun-Ae Park, Hyemin Park, Heejung Kim, Tae-Hwe Heo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
Bazedoxifene
HPV-positive
cervix cancer
EMT signaling
Online Access:https://www.mdpi.com/1422-0067/22/16/8693

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