Genomic Deletion of BAP1 and CDKN2A Are Useful Markers for Quality Control of Malignant Pleural Mesothelioma (MPM) Primary Cultures

Genomic Deletion of BAP1 and CDKN2A Are Useful Markers for Quality Control of Malignant Pleural Mesothelioma (MPM) Primary Cultures

Malignant pleural mesothelioma (MPM) is a deadly cancer that is caused by asbestos exposure and that has limited treatment options. The current standard of MPM diagnosis requires the testing of multiple immunohistochemical (IHC) markers on formalin-fixed paraffin-embedded tissue to differentiate MPM...

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Bibliographic Details
Main Authors: Kadir Harun Sarun, Kenneth Lee, Marissa Williams, Casey Maree Wright, Candice Julie Clarke, Ngan Ching Cheng, Ken Takahashi, Yuen Yee Cheng
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
mesothelioma
biomarker
FISH
genomic deletion
copy number variation
ddPCR
Online Access:http://www.mdpi.com/1422-0067/19/10/3056

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