An Enflammatory Marker in Chronic Renal Failure Patients: Visfatin
Aim: Visfatin is a cytokine released from adipose tissue, especially in enflammation. In our study, we tried to show the relationship of visfatin levels with chronic renal failure (CRF) as an enflammatory marker. Methods: We included 50 CRF patients (28 male, 22 female) who attended Uludağ Univ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2010-12-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | http://www.hasekidergisi.com/makale_9698/Kronik-Bobrek-Yetmezligi-Hastalarinda-Enflamatuvar-Bir-Belirtec-Visfatin |
| Summary: | Aim: Visfatin is a cytokine released from adipose tissue,
especially in enflammation. In our study, we tried to show the
relationship of visfatin levels with chronic renal failure (CRF) as
an enflammatory marker.
Methods: We included 50 CRF patients (28 male, 22 female)
who attended Uludağ University Nephrology Clinic and 31
healthy volunteers (13 male, 18 female). Visfatin levels and
biochemical parameters, such as parathyroid hormone (PTH),
lipid parameters, albumin, C-reactive protein (CRP), creatinine,
urea, immunoglobulins, etc. were examined.
Results: In CRF patients, visfatin levels were found to be
significantly increased (p<0.001) and albumin, hemoglobin, body
mass index (BMI) and high density lipoprotein (HDL) cholesterol
levels were decreased (p<0.001). Triglycerides (p=0.003), CPR
(p=0.005), procalcitonin (p<0.001), IgG3 (p=0.003), and ferritin
(p<0.001) levels were significantly higher in patient group than in
control group as an enflammatory marker.
Conclusion: CRF is an independent enflammatory process.
Visfatin levels in patients with chronic renal failure patients are
determined to be high as an indicator of enflammation. (The Medical
Bulletin of Haseki 2013; 53: 187-91) |
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| ISSN: | 1302-0072 2147-2688 |