Absence of a significant pharmacokinetic interaction between atorvastatin and fenofibrate: A randomized, crossover, study of a fixed-dose formulation in healthy Mexican subjects

Absence of a significant pharmacokinetic interaction between atorvastatin and fenofibrate: A randomized, crossover, study of a fixed-dose formulation in healthy Mexican subjects

Several clinical trials have substantiated the efficacy of the co-administration of statins like atorvastatin and fibrates. Without information currently available about the interaction between the two drugs, a pharmacokinetic study was conducted to investigate the effect when both drugs were co-adm...

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Bibliographic Details
Main Authors: Omar ePatiño-Rodríguez, Rosa María eMartínez-Medina, Irma eTorres-Roque, Maricela eMartínez-Delgado, America Susana Mares-Garcia, Abraham eEscobedo-Moratilla, Amador eCovarrubias-Pinedo, Angélica eArzola-Paniagua, José Luis eHerrera-Torres, José ePérez-Urizar
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Pharmacology
Subjects:
Fenofibrate
atorvastatin
LC-MS-MS
combination
pharmacokinetic interaction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00004/full

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