Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory Syndrome

Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory Syndrome

COVID-19 associated multisystem inflammatory syndrome (MIS) is a rare condition mostly affecting children but also adults (MIS-A). Although severe systemic inflammation and multiorgan dysfunction are hallmarks of the syndrome, the underlying pathogenesis is unclear. We aimed to provide novel immunol...

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Bibliographic Details
Main Authors: Andreas Ronit, Sofie E. Jørgensen, Casper Roed, Robert Eriksson, Ulrik W. Iepsen, Ronni R. Plovsing, Merete Storgaard, Finn Gustafsson, Ann-Brit E. Hansen, Trine H. Mogensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
coronavirus disease 2019
multisystem inflammatory syndrome
SARS-CoV-2
whole exome sequencing
interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.718744/full

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