Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia

Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patien...

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Main Authors: Tetsuro Oikawa, Go Ito, Takayuki Hoshino, Hidehiko Koyama, Toshihiko Hanawa
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nem101
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spelling doaj-5ef89b09c06a467bb655006fad75761c2020-11-24T22:19:44ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882009-01-016337537810.1093/ecam/nem101Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional DyspepsiaTetsuro Oikawa0Go Ito1Takayuki Hoshino2Hidehiko Koyama3Toshihiko Hanawa4Oriental Medicine Research Center of the Kitasato Institute, Tokyo, JapanOriental Medicine Research Center of the Kitasato Institute, Tokyo, JapanOriental Medicine Research Center of the Kitasato Institute, Tokyo, JapanDepartment of Internal Medicine, International University of Health and Welfare Mita Hospital, JapanOriental Medicine Research Center of the Kitasato Institute, Tokyo, JapanAlthough abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patients with FD from the standpoint of bowel gas retention. The bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients was significantly higher than that in healthy subjects. Two week administration of HKT in the FD patients showed a significant decrease of GVS. Furthermore, gastrointestinal symptoms, especially symptoms of abdominal pain, indigestion and constipation, all of which are closely related to abdominal bloating, improved significantly in FD patients after the administration of HKT. These results suggest that HKT improves abdominal bloating accompanied by the reduction of bowel gas in FD patients.http://dx.doi.org/10.1093/ecam/nem101
collection DOAJ
language English
format Article
sources DOAJ
author Tetsuro Oikawa
Go Ito
Takayuki Hoshino
Hidehiko Koyama
Toshihiko Hanawa
spellingShingle Tetsuro Oikawa
Go Ito
Takayuki Hoshino
Hidehiko Koyama
Toshihiko Hanawa
Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
Evidence-Based Complementary and Alternative Medicine
author_facet Tetsuro Oikawa
Go Ito
Takayuki Hoshino
Hidehiko Koyama
Toshihiko Hanawa
author_sort Tetsuro Oikawa
title Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_short Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_full Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_fullStr Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_full_unstemmed Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_sort hangekobokuto (banxia-houpo-tang), a kampo medicine that treats functional dyspepsia
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2009-01-01
description Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patients with FD from the standpoint of bowel gas retention. The bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients was significantly higher than that in healthy subjects. Two week administration of HKT in the FD patients showed a significant decrease of GVS. Furthermore, gastrointestinal symptoms, especially symptoms of abdominal pain, indigestion and constipation, all of which are closely related to abdominal bloating, improved significantly in FD patients after the administration of HKT. These results suggest that HKT improves abdominal bloating accompanied by the reduction of bowel gas in FD patients.
url http://dx.doi.org/10.1093/ecam/nem101
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