Qingchang Huashi granule ameliorates experimental colitis via restoring the dendritic cell-mediated Th17/Treg balance

Qingchang Huashi granule ameliorates experimental colitis via restoring the dendritic cell-mediated Th17/Treg balance

Abstract Background The balance between T helper 17 (Th17) cells and regulatory T cells (Tregs) is involved in immunological tolerance. Destruction of immunological tolerance by dendritic cell (DC)-mediated T cells is involved in the pathogenesis of ulcerative colitis (UC). Qingchang Huashi granule...

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Bibliographic Details
Main Authors: Jia Jia, Kai Zheng, Hong Shen, Jiangyi Yu, Ping Zhu, Shihai Yan, Yi Xu, Lei Zhu, Yuelin Lu, Peiqing Gu, Wan Feng
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Ulcerative colitis
Chinese medicine
T helper 17
Regulatory T cells
Dendritic cells
Immunological tolerance
Online Access:http://link.springer.com/article/10.1186/s12906-020-03088-y

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