Morphometry of Villous Membrane of Placenta at high and low Altitudes
Background: This cross sectional study was designed to compare the histomorphological characteristics of human placenta at low and high altitudes, with special reference to villous membrane. It was a cross sectional comparative study, conducted at Anatomy department of Army Medical College Rawalpin...
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doaj-5f2567b57d544af5897c398f799acd782020-11-25T03:39:16ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702009-12-01122Morphometry of Villous Membrane of Placenta at high and low AltitudesZarmina Saga0Department of Anatomy, Rawalpindi Medical College Background: This cross sectional study was designed to compare the histomorphological characteristics of human placenta at low and high altitudes, with special reference to villous membrane. It was a cross sectional comparative study, conducted at Anatomy department of Army Medical College Rawalpindi, from October 2002 to April 2003. Methods: Forty placentae were collected from normal cases at Rawalpindi (low altitude/ LA) and 40 were collected at Skardu (high altitude/HA). Samples of placental tissue were taken and processed. Histological study was done in H & E and PAS stained sections. Detailed morphology of terminal villi and villous membrane was studied. Thickness of villous membrane was measured which has not been mentioned in previous studies. Results: Mean value of villous membrane thickness in LA and HA groups was 2.188 + 0.023 m and 2.027 + 0.020 m respectively. The quantitative difference between mean thickness of villous membrane in LA and HA groups was statistically significant Conclusion: Thickness of villous membrane was significantly less in high altitude group probably showing adaptive changes to overcome the effect of reduced oxygen tension. https://www.journalrmc.com/index.php/JRMC/article/view/744High Altitudeterminal villi,villous membrane |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zarmina Saga |
spellingShingle |
Zarmina Saga Morphometry of Villous Membrane of Placenta at high and low Altitudes Journal of Rawalpindi Medical College High Altitude terminal villi, villous membrane |
author_facet |
Zarmina Saga |
author_sort |
Zarmina Saga |
title |
Morphometry of Villous Membrane of Placenta at high and low Altitudes |
title_short |
Morphometry of Villous Membrane of Placenta at high and low Altitudes |
title_full |
Morphometry of Villous Membrane of Placenta at high and low Altitudes |
title_fullStr |
Morphometry of Villous Membrane of Placenta at high and low Altitudes |
title_full_unstemmed |
Morphometry of Villous Membrane of Placenta at high and low Altitudes |
title_sort |
morphometry of villous membrane of placenta at high and low altitudes |
publisher |
Rawalpindi Medical University |
series |
Journal of Rawalpindi Medical College |
issn |
1683-3562 1683-3570 |
publishDate |
2009-12-01 |
description |
Background: This cross sectional study was designed
to compare the histomorphological characteristics of
human placenta at low and high altitudes, with special
reference to villous membrane. It was a cross sectional
comparative study, conducted at Anatomy department of
Army Medical College Rawalpindi, from October 2002 to
April 2003.
Methods: Forty placentae were collected from normal
cases at Rawalpindi (low altitude/ LA) and 40 were
collected at Skardu (high altitude/HA). Samples of
placental tissue were taken and processed. Histological
study was done in H & E and PAS stained sections.
Detailed morphology of terminal villi and villous
membrane was studied. Thickness of villous membrane
was measured which has not been mentioned in previous
studies.
Results: Mean value of villous membrane thickness in
LA and HA groups was 2.188 + 0.023 m and 2.027 + 0.020
m respectively. The quantitative difference between
mean thickness of villous membrane in LA and HA groups
was statistically significant
Conclusion: Thickness of villous membrane was
significantly less in high altitude group probably showing
adaptive changes to overcome the effect of reduced
oxygen tension.
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topic |
High Altitude terminal villi, villous membrane |
url |
https://www.journalrmc.com/index.php/JRMC/article/view/744 |
work_keys_str_mv |
AT zarminasaga morphometryofvillousmembraneofplacentaathighandlowaltitudes |
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1724539957931933696 |