Glutamate is an essential mediator in glutamine‐amplified insulin secretion

Glutamate is an essential mediator in glutamine‐amplified insulin secretion

Abstract Aims/Introduction Glutamine is the most abundant amino acid in the circulation. In this study, we investigated cell signaling in the amplification of insulin secretion by glutamine. Materials and Methods Clonal pancreatic β‐cells MIN6‐K8, wild‐type B6 mouse islets, glutamate dehydrogenase (...

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Bibliographic Details
Main Authors: Guirong Han, Harumi Takahashi, Naoya Murao, Ghupurjan Gheni, Norihide Yokoi, Yoshiyuki Hamamoto, Shun‐ichiro Asahara, Yutaka Seino, Yoshiaki Kido, Susumu Seino
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Journal of Diabetes Investigation
Subjects:
Glutamine
Glutamate
Insulin secretion
Online Access:https://doi.org/10.1111/jdi.13497

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