High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses.

High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses.

Dengue virus is a mosquito-borne flavivirus that has a large impact in global health. It is considered as one of the medically important arboviruses, and developing a preventive or therapeutic solution remains a top priority in the medical and scientific community. Drug discovery programs for potent...

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Bibliographic Details
Main Authors: Deu John M Cruz, Andrea Cristine Koishi, Juliana Bosso Taniguchi, Xiaolan Li, Rafaela Milan Bonotto, Joo Hwan No, Keum Hyun Kim, Sungmin Baek, Hee Young Kim, Marc Peter Windisch, Ana Luiza Pamplona Mosimann, Luana de Borba, Michel Liuzzi, Michael Adsetts Edberg Hansen, Claudia Nunes Duarte dos Santos, Lucio Holanda Freitas-Junior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3578765?pdf=render

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