Bone Marrow-Derived and Elicited Peritoneal Macrophages Are Not Created Equal: The Questions Asked Dictate the Cell Type Used

Bone Marrow-Derived and Elicited Peritoneal Macrophages Are Not Created Equal: The Questions Asked Dictate the Cell Type Used

Macrophages are a heterogeneous and plastic population of cells whose phenotype changes in response to their environment. Macrophage biologists utilize peritoneal (pMAC) and bone marrow-derived macrophages (BMDM) for in vitro studies. Given that pMACs mature in vivo while BMDM are ex vivo differenti...

Full description

Bibliographic Details
Main Authors: Cheryl M. Zajd, Alexis M. Ziemba, Grace M. Miralles, Terry Nguyen, Paul J. Feustel, Stanley M. Dunn, Ryan J. Gilbert, Michelle R. Lennartz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
peritoneal macrophages
bone marrow-derived macrophages
polarization
cytokines
phagocytosis
flow cytometry
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00269/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00269/full

Similar Items