Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets
Brachiaria decumbens is a highly productive tropical grass used for ruminant production. However, it can cause hepatogenous photosensitization, general ill-thrift, and deaths in ruminants due to the presence of steroidal saponins. This study determined the acute and chronic clinico-pathological resp...
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Assiut University
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doaj-5f7bdb1ddeb7461fa6f6bb9a0e15630f2021-07-10T08:42:17ZengAssiut UniversityJournal of Advanced Veterinary Research2090-62692090-62772021-07-01113167173699Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens DietsKalai Vaani Muniandy0Eric Lim Teik Chung1Mohd Farhan Hanif Reduan2Bura Thlama Paul3Mimi Syazwani Jaapar4Muhammad Hazziq Mohd Hamdan5Faez Firdaus Abdullah Jesse6Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.Department of Paraclinical Studies, Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, Pengkalan Chepa 16100, Kota Bharu, Kelantan, Malaysia.Veterinary Teaching Hospital, Faculty of Veterinary Medicine, University of Maiduguri, 600230 Maiduguri, Borno State, Nigeria.Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.Brachiaria decumbens is a highly productive tropical grass used for ruminant production. However, it can cause hepatogenous photosensitization, general ill-thrift, and deaths in ruminants due to the presence of steroidal saponins. This study determined the acute and chronic clinico-pathological responses of sheep to graded levels of B. decumbens diet. A total of 30 male crossbred Dorper sheep (six-month-old) used in the study were randomly divided into three treatment groups of 10 sheep each. Treatment 1 (T1), which served as the control group, was fed with Pennisetum purpureum and concentrates, whereas Treatments 2 (T2) and 3 (T3) were fed low (10%) and high (60%) levels of B. decumbens, respectively. The study period was divided into acute (7 days) and chronic (90 days) phases. The rectal temperature, respiratory rate, heart rate, and mucous membrane color were monitored throughout the experiment. At the end of each stage, five animals were selected from each treatment group and euthanized by slaughter to collect organs for gross pathology, organ morphometric and histopathological evaluations. The treated animals did not show significant changes (p>0.05) in rectal temperature, pulse, and respiration rates throughout the study period. However, the mucous membranes were noticeably becoming pale starting from day 60 to 90 in T3 and during the chronic phase (day 90) in T2. There was no lesion or morphometric change in any organ at postmortem examination. At histopathology, both T2 and T3 exhibited mild to moderate necrosis, hemorrhage, congestion, hydropic degeneration and edema (p<0.05) in the liver and brain. In summary, this study has established that both low and high levels of B. decumbens diets cause chronic brain and liver damages in the sheep model. This study can be used for future research on the effects of B. decumbens on grazing animals.https://advetresearch.com/index.php/AVR/article/view/735brachiaria decumbensclinical signsgross pathologyhistopathologyorgan morphometricsheep |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kalai Vaani Muniandy Eric Lim Teik Chung Mohd Farhan Hanif Reduan Bura Thlama Paul Mimi Syazwani Jaapar Muhammad Hazziq Mohd Hamdan Faez Firdaus Abdullah Jesse |
spellingShingle |
Kalai Vaani Muniandy Eric Lim Teik Chung Mohd Farhan Hanif Reduan Bura Thlama Paul Mimi Syazwani Jaapar Muhammad Hazziq Mohd Hamdan Faez Firdaus Abdullah Jesse Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets Journal of Advanced Veterinary Research brachiaria decumbens clinical signs gross pathology histopathology organ morphometric sheep |
author_facet |
Kalai Vaani Muniandy Eric Lim Teik Chung Mohd Farhan Hanif Reduan Bura Thlama Paul Mimi Syazwani Jaapar Muhammad Hazziq Mohd Hamdan Faez Firdaus Abdullah Jesse |
author_sort |
Kalai Vaani Muniandy |
title |
Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets |
title_short |
Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets |
title_full |
Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets |
title_fullStr |
Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets |
title_full_unstemmed |
Clinico-Pathological Responses of Sheep to Graded Levels of Brachiaria decumbens Diets |
title_sort |
clinico-pathological responses of sheep to graded levels of brachiaria decumbens diets |
publisher |
Assiut University |
series |
Journal of Advanced Veterinary Research |
issn |
2090-6269 2090-6277 |
publishDate |
2021-07-01 |
description |
Brachiaria decumbens is a highly productive tropical grass used for ruminant production. However, it can cause hepatogenous photosensitization, general ill-thrift, and deaths in ruminants due to the presence of steroidal saponins. This study determined the acute and chronic clinico-pathological responses of sheep to graded levels of B. decumbens diet. A total of 30 male crossbred Dorper sheep (six-month-old) used in the study were randomly divided into three treatment groups of 10 sheep each. Treatment 1 (T1), which served as the control group, was fed with Pennisetum purpureum and concentrates, whereas Treatments 2 (T2) and 3 (T3) were fed low (10%) and high (60%) levels of B. decumbens, respectively. The study period was divided into acute (7 days) and chronic (90 days) phases. The rectal temperature, respiratory rate, heart rate, and mucous membrane color were monitored throughout the experiment. At the end of each stage, five animals were selected from each treatment group and euthanized by slaughter to collect organs for gross pathology, organ morphometric and histopathological evaluations. The treated animals did not show significant changes (p>0.05) in rectal temperature, pulse, and respiration rates throughout the study period. However, the mucous membranes were noticeably becoming pale starting from day 60 to 90 in T3 and during the chronic phase (day 90) in T2. There was no lesion or morphometric change in any organ at postmortem examination. At histopathology, both T2 and T3 exhibited mild to moderate necrosis, hemorrhage, congestion, hydropic degeneration and edema (p<0.05) in the liver and brain. In summary, this study has established that both low and high levels of B. decumbens diets cause chronic brain and liver damages in the sheep model. This study can be used for future research on the effects of B. decumbens on grazing animals. |
topic |
brachiaria decumbens clinical signs gross pathology histopathology organ morphometric sheep |
url |
https://advetresearch.com/index.php/AVR/article/view/735 |
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