Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice

Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice

Myeloperoxidase (MPO) activity has been associated with the metabolic syndrome, cardiovascular and liver disease. Here, we evaluate the therapeutic potential of MPO inhibition on nonalcoholic steatohepatitis (NASH) and NASH‐induced fibrosis, the main determinant of outcomes. MPO plasma levels were e...

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Bibliographic Details
Main Authors: Anja Christina Koop, Nina Doreen Thiele, David Steins, Erik Michaëlsson, Malte Wehmeyer, Ludger Scheja, Babett Steglich, Samuel Huber, Julian Schulze zur Wiesch, Ansgar W. Lohse, Jörg Heeren, Johannes Kluwe
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1566

Internet

https://doi.org/10.1002/hep4.1566

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