Whole Transcriptome Amplification for Gene Expression Profiling and Development of Molecular Archives

Whole Transcriptome Amplification for Gene Expression Profiling and Development of Molecular Archives

Expression profiling of clinically obtainable tumor specimens has been hindered by the need for microgram quantities of RNA. In vitro transcription (IVT)-based amplifications are most commonly used to amplify small quantities of RNA for microarray analysis. However, significant drawbacks exist with...

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Bibliographic Details
Main Authors: Scott A. Tomlins, Rohit Mehra, Daniel R. Rhodes, Rajal B. Shah, Mark A. Rubin, Eric Bruening, Vladimir Makarov, Arul M. Chinnaiyan
Format: Article
Language:English
Published: Elsevier 2006-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Exponential RNA amplification
whole transcriptome amplification
prostate cancer
laser capture microdissection
FFPE tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800242

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http://www.sciencedirect.com/science/article/pii/S1476558606800242

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