Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease

We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in...

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Main Authors: Jean Yves Douet, Saima Zafar, Armand Perret-Liaudet, Caroline Lacroux, Séverine Lugan, Naima Aron, Herve Cassard, Claudia Ponto, Fabien Corbière, Juan Maria Torres, Inga Zerr, Olivier Andreoletti
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2014-01-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/20/1/13-0353_article
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spelling doaj-5fc1a55d08814dbc895c7ebe76694a702020-11-25T01:58:50ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-01-0120111411710.3201/eid2001.130353Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob DiseaseJean Yves DouetSaima ZafarArmand Perret-LiaudetCaroline LacrouxSéverine LuganNaima AronHerve CassardClaudia PontoFabien CorbièreJuan Maria TorresInga ZerrOlivier AndreolettiWe report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies.https://wwwnc.cdc.gov/eid/article/20/1/13-0353_articleCreutzfeldt-JakobvCJDsCJDprionbloodinfectivity
collection DOAJ
language English
format Article
sources DOAJ
author Jean Yves Douet
Saima Zafar
Armand Perret-Liaudet
Caroline Lacroux
Séverine Lugan
Naima Aron
Herve Cassard
Claudia Ponto
Fabien Corbière
Juan Maria Torres
Inga Zerr
Olivier Andreoletti
spellingShingle Jean Yves Douet
Saima Zafar
Armand Perret-Liaudet
Caroline Lacroux
Séverine Lugan
Naima Aron
Herve Cassard
Claudia Ponto
Fabien Corbière
Juan Maria Torres
Inga Zerr
Olivier Andreoletti
Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
Emerging Infectious Diseases
Creutzfeldt-Jakob
vCJD
sCJD
prion
blood
infectivity
author_facet Jean Yves Douet
Saima Zafar
Armand Perret-Liaudet
Caroline Lacroux
Séverine Lugan
Naima Aron
Herve Cassard
Claudia Ponto
Fabien Corbière
Juan Maria Torres
Inga Zerr
Olivier Andreoletti
author_sort Jean Yves Douet
title Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
title_short Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
title_full Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
title_fullStr Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
title_full_unstemmed Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
title_sort detection of infectivity in blood of persons with variant and sporadic creutzfeldt-jakob disease
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2014-01-01
description We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies.
topic Creutzfeldt-Jakob
vCJD
sCJD
prion
blood
infectivity
url https://wwwnc.cdc.gov/eid/article/20/1/13-0353_article
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