Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas
<p><strong>Objective</strong> To analyze the imaging characteristics of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas, so as to improve the differential diagnosis between them. <strong>Methods</strong> A retrospective analysis was c...
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doaj-5fd97533439e4fce9b8c7d72e5d1625a2020-11-24T21:27:40ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312014-09-011497897941033Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomasGui-nü HE0Xiong HAN1En-feng WANG2Li-mei WANG3Li-pin YUAN4Yan-wei LI5Xi YAN6Department of Neurology, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan, ChinaDepartment of Neurology, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan, ChinaDepartment of Radioloy, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan, ChinaDepartment of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, ChinaDepartment of Neurology, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan, ChinaDepartment of Neurology, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan, ChinaDepartment of Neurology, People's Hospital of Zhengzhou University, Zhengzhou 450003, Henan, China<p><strong>Objective</strong> To analyze the imaging characteristics of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas, so as to improve the differential diagnosis between them. <strong>Methods</strong> A retrospective analysis was conducted using clinical and MRI data from 22 cases of cervical spinal cord demyelinating diseases and 16 cases of cervical intramedullary gliomas. <strong> Results</strong> Clinical features in both groups included paresthesia [77.27% (17/22), 12/16], weakness of limbs [72.73% (16/22), 10/16], and dysfunction of autonomic nerve [45.45% (10/22), 4/16]. In cervical MRI, the lesions involving more than 3 vertebras were 63.64% (14/22) in demyelinating group and 15/16 in glioma group, and the average lengths of lesions were (3.41 ± 1.74) and (3.59 ± 1.28) vertebras in 2 groups. The lesions showed long T<sub>1</sub> signal [68.18% (15/22), 7/16], equisignal T<sub>1</sub> [31.82% (7/22), 6/16] and long T<sub>2</sub> signal [100% (22/22), 8/15] in 2 groups. Mixed T<sub>1</sub> and T<sub>2</sub> signals (3/16, 6/15) could be seen in glioma group. Demyelinating lesions had unclear boundary [90.91% (20/22)] with patchy and ribbon-like enhancement (13/16). Limited enlargement of spinal cord (15/16) and thickening spinal meninges (14/16) were more common in glioma group, usually with block and circular enhancement (12/16). Spinal cord involvement around central canal could be seen (14/15), and the cysts or central canal enlargement, hemorrhage and "cap sign" were showed frequently (7/16, 5/16 and 4/16). <strong>Conclusions</strong> Although none of one single clinical or MRI feature was sufficient enough to identify cervical spinal demyelinating diseases from cervical glioma, the comprehensive analysis of multiple features could help to make differential diagnosis of these diseases.</p><p> </p><p>doi: 10.3969/j.issn.1672-6731.2014.09.008</p>http://www.cjcnn.org/index.php/cjcnn/article/view/1037Demyelinating diseasesGliomaSpinal cordMagnetic resonance imagingDiagnosis, differential |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gui-nü HE Xiong HAN En-feng WANG Li-mei WANG Li-pin YUAN Yan-wei LI Xi YAN |
spellingShingle |
Gui-nü HE Xiong HAN En-feng WANG Li-mei WANG Li-pin YUAN Yan-wei LI Xi YAN Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas Chinese Journal of Contemporary Neurology and Neurosurgery Demyelinating diseases Glioma Spinal cord Magnetic resonance imaging Diagnosis, differential |
author_facet |
Gui-nü HE Xiong HAN En-feng WANG Li-mei WANG Li-pin YUAN Yan-wei LI Xi YAN |
author_sort |
Gui-nü HE |
title |
Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas |
title_short |
Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas |
title_full |
Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas |
title_fullStr |
Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas |
title_full_unstemmed |
Differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas |
title_sort |
differential diagnosis of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas |
publisher |
Tianjin Huanhu Hospital |
series |
Chinese Journal of Contemporary Neurology and Neurosurgery |
issn |
1672-6731 |
publishDate |
2014-09-01 |
description |
<p><strong>Objective</strong> To analyze the imaging characteristics of cervical spinal cord demyelinating diseases and cervical intramedullary gliomas, so as to improve the differential diagnosis between them. <strong>Methods</strong> A retrospective analysis was conducted using clinical and MRI data from 22 cases of cervical spinal cord demyelinating diseases and 16 cases of cervical intramedullary gliomas. <strong> Results</strong> Clinical features in both groups included paresthesia [77.27% (17/22), 12/16], weakness of limbs [72.73% (16/22), 10/16], and dysfunction of autonomic nerve [45.45% (10/22), 4/16]. In cervical MRI, the lesions involving more than 3 vertebras were 63.64% (14/22) in demyelinating group and 15/16 in glioma group, and the average lengths of lesions were (3.41 ± 1.74) and (3.59 ± 1.28) vertebras in 2 groups. The lesions showed long T<sub>1</sub> signal [68.18% (15/22), 7/16], equisignal T<sub>1</sub> [31.82% (7/22), 6/16] and long T<sub>2</sub> signal [100% (22/22), 8/15] in 2 groups. Mixed T<sub>1</sub> and T<sub>2</sub> signals (3/16, 6/15) could be seen in glioma group. Demyelinating lesions had unclear boundary [90.91% (20/22)] with patchy and ribbon-like enhancement (13/16). Limited enlargement of spinal cord (15/16) and thickening spinal meninges (14/16) were more common in glioma group, usually with block and circular enhancement (12/16). Spinal cord involvement around central canal could be seen (14/15), and the cysts or central canal enlargement, hemorrhage and "cap sign" were showed frequently (7/16, 5/16 and 4/16). <strong>Conclusions</strong> Although none of one single clinical or MRI feature was sufficient enough to identify cervical spinal demyelinating diseases from cervical glioma, the comprehensive analysis of multiple features could help to make differential diagnosis of these diseases.</p><p> </p><p>doi: 10.3969/j.issn.1672-6731.2014.09.008</p> |
topic |
Demyelinating diseases Glioma Spinal cord Magnetic resonance imaging Diagnosis, differential |
url |
http://www.cjcnn.org/index.php/cjcnn/article/view/1037 |
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