Enhanced Autophagy in GAB1-Deficient Vascular Endothelial Cells Is Responsible for Atherosclerosis Progression

Enhanced Autophagy in GAB1-Deficient Vascular Endothelial Cells Is Responsible for Atherosclerosis Progression

Autophagy is a host machinery that controls cellular health. Dysfunction of autophagy is responsible for the pathogenesis of many human diseases that include atherosclerosis obliterans (ASO). Physiologically, host autophagy removes aging organelles and delays the formation of atherosclerotic plaque....

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Bibliographic Details
Main Authors: Xin Qian, Han Wang, Yuli Wang, Jiaquan Chen, Xiangjiang Guo, Haoyu Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Physiology
Subjects:
Gab1
autophagy
endothelia cell
atherosclerosis
peripheral artery disease (PAD)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.559396/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.559396/full

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