Interpreting scratch assays using pair density dynamics and approximate Bayesian computation

Quantifying the impact of biochemical compounds on collective cell spreading is an essential element of drug design, with various applications including developing treatments for chronic wounds and cancer. Scratch assays are a technically simple and inexpensive method used to study collective cell s...

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Bibliographic Details
Main Authors: Stuart T. Johnston, Matthew J. Simpson, D. L. Sean McElwain, Benjamin J. Binder, Joshua V. Ross
Format: Article
Language:English
Published: The Royal Society 2014-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.140097