Severe Anaphylactic Reaction with Ferric Carboxy Maltose: A Case Report

• Main Authors: Nalini Sharma, Lalnunnem Jion Thiek, Roma Jethani, Dina Aisha Khan, Jamil Mohammad
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2018-05-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: anaphylaxis reaction; blood parameters; side effects
• Online Access: https://jcdr.net/articles/PDF/11494/35875_CE[Ra]_F(P)_PF1(MLS_SHU)_PFA(MLS_SHU)_PB(MLS_SHU)_PN(SL).pdf

Iron deficiency is one of the commonest nutritional deficiencies among women of child bearing age, in both the developed and developing world. Iron deficiency anaemia is potentially preventable as well as treatable with the use of various iron preparations. Of all the injectable iron formulations Ferric Carboxy Maltose (FCM) has best efficacy and safety profile, however, rare adverse events can occur which should always be borne in mind. The index case is a 30-year-old women G4P2L2A1 attended casualty with bleeding per vaginum. Suction and evacuation was done for incomplete abortion. Patient received FCM after two weeks for moderate anaemia. She developed anaphylactic shock within five minutes of starting the drug. Patient was managed symptomatically with inotropes and blood transfusion. She recovered fully and was discharged well. Reports of severe anaphylactic reactions with the use of FCM are less but not absent thus, judicious and cautious use of the preparation is warranted.