Case Report: Sustained Remission Due to PD-1-Inhibition in a Metastatic Melanoma Patient With Depleted B Cells
IntroductionCheckpoint-Inhibition (CPI) with PD-1- and PD-L1-inhibitors is a well-established therapy for advanced stage melanoma patients. CPI mainly acts via T-lymphocytes. However, recent literature suggests also a role for B cells modulating its efficacy and tolerability of CPI.Case ReportWe rep...
Main Authors: | Lena Margarethe Wulfken, Jürgen Christian Becker, Rami Hayajneh, Annette Doris Wagner, Katrin Schaper-Gerhardt, Nina Flatt, Imke Grimmelmann, Ralf Gutzmer |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.733961/full |
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