Anaemia and chronic heart failure
Currently, one of the important clinical issues is the combination of chronic heart failure (CHF) and anaemia, which aggravates CHF course and prognosis. The main pathogenetic mechanism of anaemia development in CHF is absolute or relative erythropoietin deficit, due to pro-inflammatory cytokine eff...
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«SILICEA-POLIGRAF» LLC
2010-08-01
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Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2113 |
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doaj-6063ae2cdd484bf1be7d871f2536f6682021-07-28T13:50:51Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252010-08-01941161231822Anaemia and chronic heart failureT. A. Kazantseva0Radjesh Radjan1M. A. Efremovtseva2L. G. Alexandriya3Zh. D. Kobalava4V. S. Moiseev5Russian University of People’s Friendship. MoscowRussian University of People’s Friendship. MoscowRussian University of People’s Friendship. MoscowRussian University of People’s Friendship. MoscowRussian University of People’s Friendship. MoscowRussian University of People’s Friendship. MoscowCurrently, one of the important clinical issues is the combination of chronic heart failure (CHF) and anaemia, which aggravates CHF course and prognosis. The main pathogenetic mechanism of anaemia development in CHF is absolute or relative erythropoietin deficit, due to pro-inflammatory cytokine effects, and renal dysfunction. The recent studies have demonstrated that correcting even moderate anaemia in CHF results in increased exercise tolerance, reduced NYHA functional class, improved quality of life, cardiac morphology and function, decreased need for diuretics, and reduced hospitalization incidence. However, there are no available data on anaemia correction effects on long-term survival, as well as on haemoglobin levels needed to start the anaemia treatment, or safe target levels of haemoglobin.https://cardiovascular.elpub.ru/jour/article/view/2113anaemiachronic heart failurechronic kidney diseaseiron deficiency anaemiaerythropoietin |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
T. A. Kazantseva Radjesh Radjan M. A. Efremovtseva L. G. Alexandriya Zh. D. Kobalava V. S. Moiseev |
spellingShingle |
T. A. Kazantseva Radjesh Radjan M. A. Efremovtseva L. G. Alexandriya Zh. D. Kobalava V. S. Moiseev Anaemia and chronic heart failure Кардиоваскулярная терапия и профилактика anaemia chronic heart failure chronic kidney disease iron deficiency anaemia erythropoietin |
author_facet |
T. A. Kazantseva Radjesh Radjan M. A. Efremovtseva L. G. Alexandriya Zh. D. Kobalava V. S. Moiseev |
author_sort |
T. A. Kazantseva |
title |
Anaemia and chronic heart failure |
title_short |
Anaemia and chronic heart failure |
title_full |
Anaemia and chronic heart failure |
title_fullStr |
Anaemia and chronic heart failure |
title_full_unstemmed |
Anaemia and chronic heart failure |
title_sort |
anaemia and chronic heart failure |
publisher |
«SILICEA-POLIGRAF» LLC |
series |
Кардиоваскулярная терапия и профилактика |
issn |
1728-8800 2619-0125 |
publishDate |
2010-08-01 |
description |
Currently, one of the important clinical issues is the combination of chronic heart failure (CHF) and anaemia, which aggravates CHF course and prognosis. The main pathogenetic mechanism of anaemia development in CHF is absolute or relative erythropoietin deficit, due to pro-inflammatory cytokine effects, and renal dysfunction. The recent studies have demonstrated that correcting even moderate anaemia in CHF results in increased exercise tolerance, reduced NYHA functional class, improved quality of life, cardiac morphology and function, decreased need for diuretics, and reduced hospitalization incidence. However, there are no available data on anaemia correction effects on long-term survival, as well as on haemoglobin levels needed to start the anaemia treatment, or safe target levels of haemoglobin. |
topic |
anaemia chronic heart failure chronic kidney disease iron deficiency anaemia erythropoietin |
url |
https://cardiovascular.elpub.ru/jour/article/view/2113 |
work_keys_str_mv |
AT takazantseva anaemiaandchronicheartfailure AT radjeshradjan anaemiaandchronicheartfailure AT maefremovtseva anaemiaandchronicheartfailure AT lgalexandriya anaemiaandchronicheartfailure AT zhdkobalava anaemiaandchronicheartfailure AT vsmoiseev anaemiaandchronicheartfailure |
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1721271235719987200 |