Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.
Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an environmental reservoir and mostly establishes chronic infections in a broad range of mammals, B. pertussis is a human-specific p...
Main Authors: | Jan Bayram, Ivana Malcova, Larisa Sinkovec, Jana Holubova, Gaia Streparola, David Jurnecka, Jan Kucera, Radislav Sedlacek, Peter Sebo, Jana Kamanova |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-08-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008512 |
Similar Items
-
Differential expression of type III effector BteA protein due to IS481 insertion in Bordetella pertussis.
by: Hyun-Ja Han, et al.
Published: (2011-01-01) -
Characterization of the N-terminal domain of BteA: a Bordetella type III secreted cytotoxic effector.
by: Chen Guttman, et al.
Published: (2013-01-01) -
BteA Secreted from the Bordetella bronchiseptica Type III Secetion System Induces Necrosis through an Actin Cytoskeleton Signaling Pathway and Inhibits Phagocytosis by Macrophages.
by: Asaomi Kuwae, et al.
Published: (2016-01-01) -
Correction: BteA Secreted from the Bordetella bronchiseptica Type III Secetion System Induces Necrosis through an Actin Cytoskeleton Signaling Pathway and Inhibits Phagocytosis by Macrophages.
by: Asaomi Kuwae, et al.
Published: (2017-01-01) -
Bordetella Type III Secretion Injectosome and Effector Proteins
by: Jana Kamanova
Published: (2020-09-01)