Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission.

Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission.

Unlike in most pathogens, multiple-strain (polygenomic) infections of P. falciparum are frequently composed of genetic siblings. These genetic siblings are the result of sexual reproduction and can coinfect the same host when cotransmitted by the same mosquito. The degree with which coinfecting stra...

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Bibliographic Details
Main Authors: Wesley Wong, Edward A Wenger, Daniel L Hartl, Dyann F Wirth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5777656?pdf=render

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