24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease

24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease

We recently found that dietary supplementation with the seaweed <i>Sargassum fusiforme</i>, containing the preferential LXRβ-agonist 24(S)-saringosterol, prevented memory decline and reduced amyloid-β (Aβ) deposition in an Alzheimer’s disease (AD) mouse model without inducing hepatic ste...

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Bibliographic Details
Main Authors: Nikita Martens, Melissa Schepers, Na Zhan, Frank Leijten, Gardi Voortman, Assia Tiane, Ben Rombaut, Janne Poisquet, Nienke van de Sande, Anja Kerksiek, Folkert Kuipers, Johan W. Jonker, Hongbing Liu, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Marine Drugs
Subjects:
Alzheimer’s disease
seaweed
<i>Sargassum fusiforme</i>
phytosterols
cholesterol metabolism
Online Access:https://www.mdpi.com/1660-3397/19/4/190

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