Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway

Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway

Abstract Background Hepatocellular carcinoma (HCC) is the fourth fatal malignant tumour type worldwide. However, the exact molecular mechanism involved in HCC progression remains unclear. Methods Three pairs of HCC and matched portal vein tumour thrombus (PVTT) tissue samples were analysed by isobar...

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Bibliographic Details
Main Authors: Bowen Yao, Yazhao Li, Tianxiang Chen, Yongshen Niu, Yufeng Wang, Yuanyuan Yang, Xinyu Wei, Qingguang Liu, Kangsheng Tu
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical and Translational Medicine
Subjects:
CFL1
hepatocellular carcinoma
hypoxic microenvironment
PLD1
Online Access:https://doi.org/10.1002/ctm2.366

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