Toxicological Assessment of Bromochlorophene: Single and Repeated-Dose 28-Day Oral Toxicity, Genotoxicity, and Dermal Application in Sprague–Dawley Rats

Toxicological Assessment of Bromochlorophene: Single and Repeated-Dose 28-Day Oral Toxicity, Genotoxicity, and Dermal Application in Sprague–Dawley Rats

Bromochlorophene (BCP) has shown good properties in sterilization and antibacterial activity and is widely used as a household chemical. We evaluated the genotoxicity, single and repeated-dose 28-day oral toxicity, and dermal application of a BCP suspension in Sprague–Dawley (SD) rats. For the singl...

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Bibliographic Details
Main Authors: Hansol Won, Da Hye Jeong, Hyo-Sook Shin, Jin Hee Lee, Jeong Pyo Lee, Jun-Young Yang, Kikyung Jung, Jayoung Jeong, Jae Ho Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
bromochlorophene
repeated-dose 28-day oral toxicity study
genotoxicity
preservative
NOAEL
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.690141/full

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