Effect of Cyclosporine on Lesion Growth and Infarct Size within the White and Gray Matter

Effect of Cyclosporine on Lesion Growth and Infarct Size within the White and Gray Matter

BackgroundIn a recent trial, cyclosporine A (CsA) failed to reduce infarct size in acute stroke patients treated with intravenous thrombolysis. White matter (WM) and gray matter (GM) may have distinct vulnerability to ischemia and response to therapy. Using final infarct size and lesion growth as en...

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Main Authors: Tae-Hee Cho, Elodie Ong, Nathan Mewton, Julien Bouvier, Fabien Chauveau, Thomas Ritzenthaler, Laura Mechtouff, Laurent Derex, Marielle Buisson, Yves Berthezène, Michel Ovize, Norbert Nighoghossian
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Neurology
Subjects:
ischemic stroke
thrombolysis
neuroprotection
recanalization
cyclosporin
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00151/full

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