Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties

Some 3-(Substituted methylthio)-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole derivatives were synthesized in six steps starting from easily accessible gallic acid. The resulting sulfides were then catalytically oxidized to the title sulfones with H2O2. The products were obtained in high yie...

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Main Authors:	Deyu Hu, Yang Song, Pinaki Bhadury, Baoan Song, Weiming Xu
Format:	Article
Language:	English
Published:	MDPI AG 2010-02-01
Series:	Molecules
Subjects:	sulfone derivatives 1,2,4-triazole sodium tungstate hydrogen peroxide synthesis crystal structure
Online Access:	http://www.mdpi.com/1420-3049/15/2/766/

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spelling	doaj-613ca4f1d2a24f9198382a5ac32d976c2020-11-25T00:21:09ZengMDPI AGMolecules1420-30492010-02-0115276677910.3390/molecules15020766Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole MoietiesDeyu HuYang SongPinaki BhaduryBaoan SongWeiming XuSome 3-(Substituted methylthio)-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole derivatives were synthesized in six steps starting from easily accessible gallic acid. The resulting sulfides were then catalytically oxidized to the title sulfones with H2O2. The products were obtained in high yield under mild conditions and practically devoid of any by-products. The structures were confirmed by elemental analysis, IR, 1H- and 13C-NMR spectral data. Furthermore, a detailed X-ray crystallography structural analysis of model triazole 7g was carried out. http://www.mdpi.com/1420-3049/15/2/766/sulfone derivatives1,2,4-triazolesodium tungstatehydrogen peroxidesynthesiscrystal structure
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Deyu Hu Yang Song Pinaki Bhadury Baoan Song Weiming Xu
spellingShingle	Deyu Hu Yang Song Pinaki Bhadury Baoan Song Weiming Xu Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties Molecules sulfone derivatives 1,2,4-triazole sodium tungstate hydrogen peroxide synthesis crystal structure
author_facet	Deyu Hu Yang Song Pinaki Bhadury Baoan Song Weiming Xu
author_sort	Deyu Hu
title	Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties
title_short	Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties
title_full	Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties
title_fullStr	Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties
title_full_unstemmed	Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties
title_sort	synthesis and crystal structure of novel sulfone derivatives containing 1,2,4-triazole moieties
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2010-02-01
description	Some 3-(Substituted methylthio)-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole derivatives were synthesized in six steps starting from easily accessible gallic acid. The resulting sulfides were then catalytically oxidized to the title sulfones with H2O2. The products were obtained in high yield under mild conditions and practically devoid of any by-products. The structures were confirmed by elemental analysis, IR, 1H- and 13C-NMR spectral data. Furthermore, a detailed X-ray crystallography structural analysis of model triazole 7g was carried out.
topic	sulfone derivatives 1,2,4-triazole sodium tungstate hydrogen peroxide synthesis crystal structure
url	http://www.mdpi.com/1420-3049/15/2/766/
work_keys_str_mv	AT deyuhu synthesisandcrystalstructureofnovelsulfonederivativescontaining124triazolemoieties AT yangsong synthesisandcrystalstructureofnovelsulfonederivativescontaining124triazolemoieties AT pinakibhadury synthesisandcrystalstructureofnovelsulfonederivativescontaining124triazolemoieties AT baoansong synthesisandcrystalstructureofnovelsulfonederivativescontaining124triazolemoieties AT weimingxu synthesisandcrystalstructureofnovelsulfonederivativescontaining124triazolemoieties
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Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties

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