Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia

Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia

Abstract Background Following acute infection, Herpes Simplex virus-1 (HSV-1) establishes lifelong latency and recurrent reactivation in the sensory neurons of trigeminal ganglia (TG). Infected tree shrew differs from mouse and show characteristics similar to human infection. A detailed transcriptom...

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Bibliographic Details
Main Authors: Erlin Wang, Yunshuang Ye, Ke Zhang, Jinlong Yang, Daohua Gong, Jianhua Zhang, Renjun Hong, Huan Zhang, Lihong Li, Guijun Chen, Liping Yang, Jianmei Liu, Hanyu Cao, Ting Du, Nigel W. Fraser, Le Cheng, Xia Cao, Jumin Zhou
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Virology Journal
Subjects:
HSV-1
Tree shrew
RNAseq
Trigeminal ganglia
Latency
Spontaneous reactivation
Online Access:http://link.springer.com/article/10.1186/s12985-020-01344-8

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