Phlebotomus perniciosus Recombinant Salivary Proteins Polarize Murine Macrophages Toward the Anti-Inflammatory Phenotype

Phlebotomus perniciosus Recombinant Salivary Proteins Polarize Murine Macrophages Toward the Anti-Inflammatory Phenotype

Phlebotomus perniciosus (Diptera: Phlebotominae) is a medically and veterinary important insect vector. It transmits the unicellular parasite Leishmania infantum that multiplies intracellularly in macrophages causing life-threatening visceral diseases. Leishmania establishment in the vertebrate host...

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Bibliographic Details
Main Authors: Petra Sumova, Nikola Polanska, Tereza Lestinova, Tatiana Spitzova, Barbora Kalouskova, Ondrej Vanek, Petr Volf, Iva Rohousova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Phlebotomus
sand fly saliva
yellow-related proteins
apyrase
macrophage polarization
immunogenicity
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00427/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00427/full

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