Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis

Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.

Bibliographic Details
Main Authors: Vincent Koo, Amgad El Mekabaty, Peter Hamilton, Perry Maxwell, Osama Sharaf, Jim Diamond, Jenny Watson, Kathleen Williamson
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0501
Description
Summary:Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.
ISSN:1570-5870
1875-8606