Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis

Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.

Bibliographic Details
Main Authors:	Vincent Koo, Amgad El Mekabaty, Peter Hamilton, Perry Maxwell, Osama Sharaf, Jim Diamond, Jenny Watson, Kathleen Williamson
Format:	Article
Language:	English
Published:	Hindawi Limited 2010-01-01
Series:	Cellular Oncology
Online Access:	http://dx.doi.org/10.3233/CLO-2009-0501

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spelling	doaj-61474e5282f1458b9aacef398fff3af62020-11-24T23:06:29ZengHindawi LimitedCellular Oncology1570-58701875-86062010-01-01321-2677610.3233/CLO-2009-0501Novel In Vitro Assays for the Characterization of EMT in TumourigenesisVincent Koo0Amgad El Mekabaty1Peter Hamilton2Perry Maxwell3Osama Sharaf4Jim Diamond5Jenny Watson6Kathleen Williamson7Uro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKUro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKBio-imaging & Informatics Research Group, Centre for Cancer Research & Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UKBelfast Health and Social Care Trust, Belfast, Northern Ireland, UKUro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKBio-imaging & Informatics Research Group, Centre for Cancer Research & Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UKThe UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, IrelandUro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKBackground: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.http://dx.doi.org/10.3233/CLO-2009-0501
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Vincent Koo Amgad El Mekabaty Peter Hamilton Perry Maxwell Osama Sharaf Jim Diamond Jenny Watson Kathleen Williamson
spellingShingle	Vincent Koo Amgad El Mekabaty Peter Hamilton Perry Maxwell Osama Sharaf Jim Diamond Jenny Watson Kathleen Williamson Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis Cellular Oncology
author_facet	Vincent Koo Amgad El Mekabaty Peter Hamilton Perry Maxwell Osama Sharaf Jim Diamond Jenny Watson Kathleen Williamson
author_sort	Vincent Koo
title	Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
title_short	Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
title_full	Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
title_fullStr	Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
title_full_unstemmed	Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
title_sort	novel in vitro assays for the characterization of emt in tumourigenesis
publisher	Hindawi Limited
series	Cellular Oncology
issn	1570-5870 1875-8606
publishDate	2010-01-01
description	Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.
url	http://dx.doi.org/10.3233/CLO-2009-0501
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Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis

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