Temporal Vestibular Deficits in synaptojanin 1 (synj1) Mutants
The lipid phosphatase synaptojanin 1 (synj1) is required for the disassembly of clathrin coats on endocytic compartments. In neurons such activity is necessary for the recycling of endocytosed membrane into synaptic vesicles. Mutations in zebrafish synj1 have been shown to disrupt the activity of ri...
Main Authors: | Yan Gao, Teresa Nicolson |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-01-01
|
Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2020.604189/full |
Similar Items
-
Evidence for a Clathrin-independent mode of endocytosis at a continuously active sensory synapse
by: Michaela eFuchs, et al.
Published: (2014-02-01) -
Synaptojanin cooperates in vivo with endophilin through an unexpected mechanism
by: Yongming Dong, et al.
Published: (2015-04-01) -
Combining data integration and molecular dynamics for target identification in α-Synuclein-aggregating neurodegenerative diseases: Structural insights on Synaptojanin-1 (Synj1)
by: Kirsten Jenkins, et al.
Published: (2020-01-01) -
Synaptojanin2 Mutation Causes Progressive High-frequency Hearing Loss in Mice
by: Elisa Martelletti, et al.
Published: (2020-09-01) -
Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish
by: Katie S. Kindt, et al.
Published: (2018-09-01)