Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes
Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms Caenorhabditis elegans, Drosophila melanogaster, Mus musculus...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-03-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340915003595 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Sadhna Phanse Cuihong Wan Blake Borgeson Fan Tu Kevin Drew Greg Clark Xuejian Xiong Olga Kagan Julian Kwan Alexandr Bezginov Kyle Chessman Swati Pal Graham Cromar Ophelia Papoulas Zuyao Ni Daniel R. Boutz Snejana Stoilova Pierre C. Havugimana Xinghua Guo Ramy H. Malty Mihail Sarov Jack Greenblatt Mohan Babu W. Brent Derry Elisabeth R. Tillier John B. Wallingford John Parkinson Edward M. Marcotte Andrew Emili |
| spellingShingle |
Sadhna Phanse Cuihong Wan Blake Borgeson Fan Tu Kevin Drew Greg Clark Xuejian Xiong Olga Kagan Julian Kwan Alexandr Bezginov Kyle Chessman Swati Pal Graham Cromar Ophelia Papoulas Zuyao Ni Daniel R. Boutz Snejana Stoilova Pierre C. Havugimana Xinghua Guo Ramy H. Malty Mihail Sarov Jack Greenblatt Mohan Babu W. Brent Derry Elisabeth R. Tillier John B. Wallingford John Parkinson Edward M. Marcotte Andrew Emili Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes Data in Brief |
| author_facet |
Sadhna Phanse Cuihong Wan Blake Borgeson Fan Tu Kevin Drew Greg Clark Xuejian Xiong Olga Kagan Julian Kwan Alexandr Bezginov Kyle Chessman Swati Pal Graham Cromar Ophelia Papoulas Zuyao Ni Daniel R. Boutz Snejana Stoilova Pierre C. Havugimana Xinghua Guo Ramy H. Malty Mihail Sarov Jack Greenblatt Mohan Babu W. Brent Derry Elisabeth R. Tillier John B. Wallingford John Parkinson Edward M. Marcotte Andrew Emili |
| author_sort |
Sadhna Phanse |
| title |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes |
| title_short |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes |
| title_full |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes |
| title_fullStr |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes |
| title_full_unstemmed |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes |
| title_sort |
proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes |
| publisher |
Elsevier |
| series |
Data in Brief |
| issn |
2352-3409 |
| publishDate |
2016-03-01 |
| description |
Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Strongylocentrotus purpuratus, and Homo sapiens. The interaction network obtained from the data was validated globally in 4 distant species (Xenopus laevis, Nematostella vectensis, Dictyostelium discoideum, Saccharomyces cerevisiae) and locally by targeted affinity-purification experiments. Here we provide details of our massive set of supporting biochemical fractionation data available via ProteomeXchange (http://www.ebi.ac.uk/pride/archive/projects/PXD002319-http://www.ebi.ac.uk/pride/archive/projects/PXD002328), PPIs via BioGRID (185267); and interaction network projections via (http://metazoa.med.utoronto.ca) made fully accessible to allow further exploration. The datasets here are related to the research article on metazoan macromolecular complexes in Nature [1]. Keywords: Proteomics, Metazoa, Protein complexes, Biochemical, Fractionation |
| url |
http://www.sciencedirect.com/science/article/pii/S2352340915003595 |
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doaj-61941f383d734062b94b7d121439c1702020-11-25T01:18:12ZengElsevierData in Brief2352-34092016-03-016715721Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexesSadhna Phanse0Cuihong Wan1Blake Borgeson2Fan Tu3Kevin Drew4Greg Clark5Xuejian Xiong6Olga Kagan7Julian Kwan8Alexandr Bezginov9Kyle Chessman10Swati Pal11Graham Cromar12Ophelia Papoulas13Zuyao Ni14Daniel R. Boutz15Snejana Stoilova16Pierre C. Havugimana17Xinghua Guo18Ramy H. Malty19Mihail Sarov20Jack Greenblatt21Mohan Babu22W. Brent Derry23Elisabeth R. Tillier24John B. Wallingford25John Parkinson26Edward M. Marcotte27Andrew Emili28Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USADonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaCenter for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USACenter for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USADepartment of Medical Biophysics, Toronto, Ontario, CanadaDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, CanadaDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, CanadaDepartment of Medical Biophysics, Toronto, Ontario, CanadaDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, CanadaCenter for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USADonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaCenter for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USADonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, CanadaDepartment of Biochemistry, University of Regina, Regina, Saskatchewan, CanadaMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, GermanyDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, CanadaDepartment of Biochemistry, University of Regina, Regina, Saskatchewan, CanadaDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Medical Biophysics, Toronto, Ontario, CanadaCenter for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USADepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, CanadaCenter for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USADonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Corresponding author at: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, CCBR, Rm 914, 160 College Street, Toronto, Ontario, Canada M5S 3E1. Tel.: +1 617 610 4042; fax: +1 416 978 8528.Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Strongylocentrotus purpuratus, and Homo sapiens. The interaction network obtained from the data was validated globally in 4 distant species (Xenopus laevis, Nematostella vectensis, Dictyostelium discoideum, Saccharomyces cerevisiae) and locally by targeted affinity-purification experiments. Here we provide details of our massive set of supporting biochemical fractionation data available via ProteomeXchange (http://www.ebi.ac.uk/pride/archive/projects/PXD002319-http://www.ebi.ac.uk/pride/archive/projects/PXD002328), PPIs via BioGRID (185267); and interaction network projections via (http://metazoa.med.utoronto.ca) made fully accessible to allow further exploration. The datasets here are related to the research article on metazoan macromolecular complexes in Nature [1]. Keywords: Proteomics, Metazoa, Protein complexes, Biochemical, Fractionationhttp://www.sciencedirect.com/science/article/pii/S2352340915003595 |