Hyperoxia-induced lung structure–function relation, vessel rarefaction, and cardiac hypertrophy in an infant rat model

Hyperoxia-induced lung structure–function relation, vessel rarefaction, and cardiac hypertrophy in an infant rat model

Abstract Background Hyperoxia-induced bronchopulmonary dysplasia (BPD) models are essential for better understanding and impacting on long-term pulmonary, cardiovascular, and neurological sequelae of this chronic disease. Only few experimental studies have systematically compared structural alterati...

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Bibliographic Details
Main Authors: Francesco Greco, Susanne Wiegert, Philipp Baumann, Sven Wellmann, Giovanni Pellegrini, Vincenzo Cannizzaro
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Translational Medicine
Subjects:
Hyperoxia
Bronchopulmonary dysplasia
Animal model
Respiratory system mechanics
Forced oscillation technique
Hysteresivity eta (η)
Online Access:http://link.springer.com/article/10.1186/s12967-019-1843-1

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