Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways.
Parasitic roundworm infections plague more than 2 billion people (1/3 of humanity) and cause drastic losses in crops and livestock. New anthelmintic drugs are urgently needed as new drug resistance and environmental concerns arise. A "chokepoint reaction" is defined as a reaction that eith...
Main Authors: | Christina M Taylor, Qi Wang, Bruce A Rosa, Stanley Ching-Cheng Huang, Kerrie Powell, Tim Schedl, Edward J Pearce, Sahar Abubucker, Makedonka Mitreva |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3731235?pdf=render |
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