MicroRNA-206 suppresses mesothelioma progression via the Ras signaling axis

MicroRNA-206 suppresses mesothelioma progression via the Ras signaling axis

Malignant pleural mesothelioma (MPM) is an incurable surface neoplasm with peculiar pathobiology. MPM proliferates by using the tyrosine-kinase-Ras pathway. Despite representing an attractive therapeutic target, there are no standard agent(s) specifically inhibiting Ras signaling adopted in clinical...

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Bibliographic Details
Main Authors: Anand Singh, Nathanael Pruett, Roma Pahwa, Arushi P. Mahajan, David S. Schrump, Chuong D. Hoang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
mesothelioma
microRNA
receptor tyrosine kinase
Ras
cell cycle
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000949

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