Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

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Background: The application of methotrexate (MTX) as a chemotherapy agent and immune system suppressant has various side effects. Crocin, a xanthine derivative plant, has many therapeutic benefits. This study was planned to assess the effect of crocin on renal toxicity of MTX in a rat model. Methods...

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Bibliographic Details
Main Authors: Cyrus Jalili, Ali Ghanbari, Shiva Roshankhah, Mohammad Reza Salahshoor
Format: Article
Language:English
Published: Pasteur Institute of Iran 2020-01-01
Series:Iranian Biomedical Journal
Subjects:
antioxidants
crocin
kidney
methotrexate
Online Access:http://ibj.pasteur.ac.ir/article-1-2868-en.html

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