Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization

Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization

Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a...

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Main Authors: Ioanna A. Comstock, Michelle Longmire, Richard H. Aster, Amin A. Milki
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2015/890610
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spelling doaj-61e47f62b88a4518aa17ce98ccdd308b2020-11-25T00:44:14ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/890610890610Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro FertilizationIoanna A. Comstock0Michelle Longmire1Richard H. Aster2Amin A. Milki3Stanford University Medical Center, 900 Welch Road, Suite 20, Palo Alto, CA 94304, USAStanford University Medical Center, 450 Broadway Street, Redwood City, CA 94063, USABloodCenter of Wisconsin, Medical College of Wisconsin, P.O. Box 2178, Milwaukee, WI 53201, USAStanford University Medical Center, 900 Welch Road, Suite 350 MC 5800, Palo Alto, CA 94304, USADrug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval. The patient was admitted to the intensive care unit for resuscitation with blood products. The presence of drug-dependent platelet antibodies to Cefazolin was confirmed serologically.http://dx.doi.org/10.1155/2015/890610
collection DOAJ
language English
format Article
sources DOAJ
author Ioanna A. Comstock
Michelle Longmire
Richard H. Aster
Amin A. Milki
spellingShingle Ioanna A. Comstock
Michelle Longmire
Richard H. Aster
Amin A. Milki
Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
Case Reports in Obstetrics and Gynecology
author_facet Ioanna A. Comstock
Michelle Longmire
Richard H. Aster
Amin A. Milki
author_sort Ioanna A. Comstock
title Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_short Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_full Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_fullStr Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_full_unstemmed Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_sort drug-induced thrombocytopenia following a transvaginal oocyte retrieval for in vitro fertilization
publisher Hindawi Limited
series Case Reports in Obstetrics and Gynecology
issn 2090-6684
2090-6692
publishDate 2015-01-01
description Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval. The patient was admitted to the intensive care unit for resuscitation with blood products. The presence of drug-dependent platelet antibodies to Cefazolin was confirmed serologically.
url http://dx.doi.org/10.1155/2015/890610
work_keys_str_mv AT ioannaacomstock druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
AT michellelongmire druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
AT richardhaster druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
AT aminamilki druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
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