Bovine Embryo-Secreted microRNA-30c Is a Potential Non-invasive Biomarker for Hampered Preimplantation Developmental Competence

Bovine Embryo-Secreted microRNA-30c Is a Potential Non-invasive Biomarker for Hampered Preimplantation Developmental Competence

Recently, secreted microRNAs (miRNAs) have received a lot of attention since they may act as autocrine factors. However, how secreted miRNAs influence embryonic development is still poorly understood. We identified 294 miRNAs, 114 known, and 180 novel, in the conditioned medium of individually cultu...

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Bibliographic Details
Main Authors: Xiaoyuan Lin, Evy Beckers, Séan Mc Cafferty, Yannick Gansemans, Katarzyna Joanna Szymańska, Krishna Chaitanya Pavani, João Portela Catani, Filip Van Nieuwerburgh, Dieter Deforce, Petra De Sutter, Ann Van Soom, Luc Peelman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
bovine embryos
secreted miRNAs
miR-30c
CDK12
cell cycle
DNA damage response
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00315/full

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