BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control

BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control

Abstract Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long‐term weight control. This is due, in part, to difficulties in identifying tolerable and efficacious small molecules or biologics capa...

Full description

Bibliographic Details
Main Authors: Christopher L Axelrod, William T King, Gangarao Davuluri, Robert C Noland, Jacob Hall, Michaela Hull, Wagner S Dantas, Elizabeth RM Zunica, Stephanie J Alexopoulos, Kyle L Hoehn, Ingeborg Langohr, Krisztian Stadler, Haylee Doyle, Eva Schmidt, Stephan Nieuwoudt, Kelly Fitzgerald, Kathryn Pergola, Hisashi Fujioka, Jacob T Mey, Ciaran Fealy, Anny Mulya, Robbie Beyl, Charles L Hoppel, John P Kirwan
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:EMBO Molecular Medicine
Subjects:
AMPK
BAM15
mitochondria
obesity
type 2 diabetes
Online Access:https://doi.org/10.15252/emmm.202012088

Similar Items

Similar Items