Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression

Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression

Mitochondrial uncoupling protein 2 (UCP2) has been well characterized to control the production of reactive oxygen species (ROS) and astrocytes are the major cells responsible for the ROS production and the inflammatory responses in the brain. However, the function of UCP2 in astrocytes and the cont...

Full description

Bibliographic Details
Main Authors: Ren-Hong Du, Fang-Fang Wu, Ming Lu, Xiao-dong Shu, Jian-Hua Ding, Guangyu Wu, Gang Hu
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Redox Biology
Subjects:
Uncoupling protein 2
NLRP3 inflammasome
Astrocyte
Depression
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716301033

Similar Items

Similar Items