Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship

<p align="center"><strong><span style="text-decoration: underline;">ABSTRACT</span></strong></p><p><strong><span style="text-decoration: underline;">Background:</span></strong><strong> </strong&g...

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Main Authors: Paul Eduardo Lada, Christian Janikow, Edgardo Corti, Nicolas Menso, Gastón Moretti, Martín Alé, Martín Sánchez
Format: Article
Language:English
Published: Universidad Nacional de Córdoba 2017-06-01
Series:Revista de la Facultad de Ciencias Médicas de Córdoba
Subjects:
Online Access:https://revistas.unc.edu.ar/index.php/med/article/view/13352
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language English
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author Paul Eduardo Lada
Christian Janikow
Edgardo Corti
Nicolas Menso
Gastón Moretti
Martín Alé
Martín Sánchez
spellingShingle Paul Eduardo Lada
Christian Janikow
Edgardo Corti
Nicolas Menso
Gastón Moretti
Martín Alé
Martín Sánchez
Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship
Revista de la Facultad de Ciencias Médicas de Córdoba
Keywords: Tokyo guidelines 2007, acute cholecystitis, chronic cholecystitis, acute exacerbation of chronic cholecystitis, pathology study of the specimen.
author_facet Paul Eduardo Lada
Christian Janikow
Edgardo Corti
Nicolas Menso
Gastón Moretti
Martín Alé
Martín Sánchez
author_sort Paul Eduardo Lada
title Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship
title_short Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship
title_full Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship
title_fullStr Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship
title_full_unstemmed Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship
title_sort useful of tokyo guidelines in the diagnosis of acute cholecystitis. anatomopathologie correlationship
publisher Universidad Nacional de Córdoba
series Revista de la Facultad de Ciencias Médicas de Córdoba
issn 0014-6722
1853-0605
publishDate 2017-06-01
description <p align="center"><strong><span style="text-decoration: underline;">ABSTRACT</span></strong></p><p><strong><span style="text-decoration: underline;">Background:</span></strong><strong> </strong>In the year 2007 a group of experts come together to discuss criteria for acute cholecystitis and to establish therapeutic guidelines and states of gravity in this disease.<strong> </strong></p><p><strong><span style="text-decoration: underline;">Objectives:</span></strong><strong> </strong>we correlated the criteria of the Tokyo Guidelines 2007 with the anatomopathology study of the surgical specimen.</p><p><strong><span style="text-decoration: underline;">Setting:</span></strong><strong> </strong>Service of Urgencies of the National Clinic Hospital in Córdoba, Argentine.</p><p><strong><span style="text-decoration: underline;">Methods:</span></strong><strong> </strong>We studied 324 patients (120 male and 204 female) older than 15 years and without limits of age with the criteria of acute cholecystitis a cord to the Tokyo guidelines 2007. 202 patients had a preoperative diagnosis of chronic cholecystitis and 89 of acute cholecystitis, all received cholecystectomy and studied the operative specimen in the anatomopathology department. Anatomopathology criteria for acute cholecystitis were the presence of polimorpho nuclear cells (PMN), for acute exacerbation of chronic cholecystitis the presence of PMN and monomorpho nuclear cells (MN), and for chronic cholecystitis the presence of MN with or without fibrosis.</p><p><strong><span style="text-decoration: underline;">Results:</span></strong><strong> </strong>This work showed 82,14% of sensitivity for the diagnostic criteria of Tokyo guidelines, 74,03% of specificity, and positive predictive value of 46%. With the Bayes Theorem the predictive value in Córdoba city was 18,49%.</p><p><strong><span style="text-decoration: underline;">Conclusion:</span></strong><strong> </strong>There is an important difference in the specificity and positive predictive value between our work and the Tokyo guidelines for acute cholecystitis. There is an important group of patients in our work with acute exacerbation of chronic cholecystitis that is not classified in the diagnostic criteria for acute cholecystitis of Tokyo guidelines.</p><p> </p><p align="center"><strong>UTILIDAD DE LAS GUIAS DE TOKIO EN LA COLECISTITIS AGUDA. </strong><strong>Correlación Anatomopatológica (Largo)</strong><strong> </strong></p><p align="center"><strong>GUIAS DE TOKIO Y COLECISTITIS AGUDA (Corto)</strong><strong> </strong></p><p><strong><span style="text-decoration: underline;">RESUMEN</span></strong></p><p><strong><span style="text-decoration: underline;">Introducción</span></strong><strong>: </strong>En el año 2007 un grupo de expertos reunidos en Tokio han ideado los criterios para el diagnóstico de colecistitis aguda con el objeto de establecer pautas terapéuticas e idear grados de gravedad en esta patología.</p><p><strong><span style="text-decoration: underline;">Material y Método:</span></strong><strong> </strong>Se estudiaron 324 pacientes (120 masculinos y 204 femeninos) mayores de 15 años sin límite de edad con los criterios diagnósticos para colecistitis aguda según las guías de Tokio 2007. Se diferenciaron 202 pacientes con diagnóstico preoperatorio de colecistitis crónica litiásica y 89 con diagnóstico de colecistitis aguda, todos sometidos a colecistectomía y a posterior se estudiaron las piezas operatorias en el departamento de anatomía patológica utilizando como criterios de colecistitis aguda la presencia de células polimorfo nucleares (PMN), de colecistitis crónica reagudizada la presencia de PMN mas mononucleares (MN), y para colecistitis crónica la presencia de MN con o sin focos de fibrosis.</p><p><strong><span style="text-decoration: underline;">Resultados:</span></strong><strong> </strong>El estudio mostró una sensibilidad del 82,14% para los criterios diagnósticos de las guías de Tokio, una especificidad del 74,03% y un valor predictivo positivo del 46%. Aplicando el Teorema de Bayes para analizar el valor predictivo, se obtuvo que el mismo sea del 18,49% en nuestra comunidad.</p><p><strong><span style="text-decoration: underline;">Conclusiones:</span></strong><strong> </strong>Existe una notoria diferencia en cuanto a la especificidad y valor predictivo positivo de los criterios de diagnóstico de CA establecidos en las guías de Tokio y las obtenidas en nuestro trabajo. Existe un grupo importante de pacientes con diagnóstico de enfermedad crónica reagudizada que no es clasificada en los trabajos de Tokio.</p>
topic Keywords: Tokyo guidelines 2007, acute cholecystitis, chronic cholecystitis, acute exacerbation of chronic cholecystitis, pathology study of the specimen.
url https://revistas.unc.edu.ar/index.php/med/article/view/13352
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spelling doaj-625ba211695948909a5fd55c9c8640972021-01-02T11:48:52ZengUniversidad Nacional de CórdobaRevista de la Facultad de Ciencias Médicas de Córdoba0014-67221853-06052017-06-01742889210.31053/1853.0605.v74.n2.1335213553Useful of Tokyo Guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationshipPaul Eduardo Lada0Christian JanikowEdgardo CortiNicolas MensoGastón MorettiMartín AléMartín SánchezSERVICIO DE GUADIA CENTRAL DEL HOSPITAL DE CLINICAS.<p align="center"><strong><span style="text-decoration: underline;">ABSTRACT</span></strong></p><p><strong><span style="text-decoration: underline;">Background:</span></strong><strong> </strong>In the year 2007 a group of experts come together to discuss criteria for acute cholecystitis and to establish therapeutic guidelines and states of gravity in this disease.<strong> </strong></p><p><strong><span style="text-decoration: underline;">Objectives:</span></strong><strong> </strong>we correlated the criteria of the Tokyo Guidelines 2007 with the anatomopathology study of the surgical specimen.</p><p><strong><span style="text-decoration: underline;">Setting:</span></strong><strong> </strong>Service of Urgencies of the National Clinic Hospital in Córdoba, Argentine.</p><p><strong><span style="text-decoration: underline;">Methods:</span></strong><strong> </strong>We studied 324 patients (120 male and 204 female) older than 15 years and without limits of age with the criteria of acute cholecystitis a cord to the Tokyo guidelines 2007. 202 patients had a preoperative diagnosis of chronic cholecystitis and 89 of acute cholecystitis, all received cholecystectomy and studied the operative specimen in the anatomopathology department. Anatomopathology criteria for acute cholecystitis were the presence of polimorpho nuclear cells (PMN), for acute exacerbation of chronic cholecystitis the presence of PMN and monomorpho nuclear cells (MN), and for chronic cholecystitis the presence of MN with or without fibrosis.</p><p><strong><span style="text-decoration: underline;">Results:</span></strong><strong> </strong>This work showed 82,14% of sensitivity for the diagnostic criteria of Tokyo guidelines, 74,03% of specificity, and positive predictive value of 46%. With the Bayes Theorem the predictive value in Córdoba city was 18,49%.</p><p><strong><span style="text-decoration: underline;">Conclusion:</span></strong><strong> </strong>There is an important difference in the specificity and positive predictive value between our work and the Tokyo guidelines for acute cholecystitis. There is an important group of patients in our work with acute exacerbation of chronic cholecystitis that is not classified in the diagnostic criteria for acute cholecystitis of Tokyo guidelines.</p><p> </p><p align="center"><strong>UTILIDAD DE LAS GUIAS DE TOKIO EN LA COLECISTITIS AGUDA. </strong><strong>Correlación Anatomopatológica (Largo)</strong><strong> </strong></p><p align="center"><strong>GUIAS DE TOKIO Y COLECISTITIS AGUDA (Corto)</strong><strong> </strong></p><p><strong><span style="text-decoration: underline;">RESUMEN</span></strong></p><p><strong><span style="text-decoration: underline;">Introducción</span></strong><strong>: </strong>En el año 2007 un grupo de expertos reunidos en Tokio han ideado los criterios para el diagnóstico de colecistitis aguda con el objeto de establecer pautas terapéuticas e idear grados de gravedad en esta patología.</p><p><strong><span style="text-decoration: underline;">Material y Método:</span></strong><strong> </strong>Se estudiaron 324 pacientes (120 masculinos y 204 femeninos) mayores de 15 años sin límite de edad con los criterios diagnósticos para colecistitis aguda según las guías de Tokio 2007. Se diferenciaron 202 pacientes con diagnóstico preoperatorio de colecistitis crónica litiásica y 89 con diagnóstico de colecistitis aguda, todos sometidos a colecistectomía y a posterior se estudiaron las piezas operatorias en el departamento de anatomía patológica utilizando como criterios de colecistitis aguda la presencia de células polimorfo nucleares (PMN), de colecistitis crónica reagudizada la presencia de PMN mas mononucleares (MN), y para colecistitis crónica la presencia de MN con o sin focos de fibrosis.</p><p><strong><span style="text-decoration: underline;">Resultados:</span></strong><strong> </strong>El estudio mostró una sensibilidad del 82,14% para los criterios diagnósticos de las guías de Tokio, una especificidad del 74,03% y un valor predictivo positivo del 46%. Aplicando el Teorema de Bayes para analizar el valor predictivo, se obtuvo que el mismo sea del 18,49% en nuestra comunidad.</p><p><strong><span style="text-decoration: underline;">Conclusiones:</span></strong><strong> </strong>Existe una notoria diferencia en cuanto a la especificidad y valor predictivo positivo de los criterios de diagnóstico de CA establecidos en las guías de Tokio y las obtenidas en nuestro trabajo. Existe un grupo importante de pacientes con diagnóstico de enfermedad crónica reagudizada que no es clasificada en los trabajos de Tokio.</p>https://revistas.unc.edu.ar/index.php/med/article/view/13352Keywords: Tokyo guidelines 2007, acute cholecystitis, chronic cholecystitis, acute exacerbation of chronic cholecystitis, pathology study of the specimen.