Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?

Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?

Clinical pharmacology of ACE inhibitors is described, comparing pharmacological effects of agents with or without sulfhydryl groups in their molecules. Sulfhydryl group-containing ACE inhibitors – captopril and especially zofenopril – are characterized by greater antioxidant properties and, potentia...

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Main Authors: D. V. Preobrazhensky, B. A. Sidorenko, S. A. S.A. Pataraya, A. V. Skorik
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2008-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
ace inhibitor
captopril
zofenopril
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1097
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spelling doaj-6287b1f1cd99427b85e5e716224a4cec2021-07-28T13:50:46Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-02-0171116123809Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?D. V. Preobrazhensky0B. A. Sidorenko1S. A. S.A. Pataraya2A. V. Skorik3I.M. Sechenov Moscow Medical Academy; Education and Research Medical Center, RF President’s AdministrationEducation and Research Medical Center, RF President’s AdministrationEducation and Research Medical Center, RF President’s AdministrationCentral Clinical Hospital, RF President’s Administration. MoscowClinical pharmacology of ACE inhibitors is described, comparing pharmacological effects of agents with or without sulfhydryl groups in their molecules. Sulfhydryl group-containing ACE inhibitors – captopril and especially zofenopril – are characterized by greater antioxidant properties and, potentially, stronger cardio- and vasoprotective action. Literature data confirm benefits of these sulfhydryl ACE inhibitors as first-line medications for treating acute myocardial infarction, other coronary heart disease forms, arterial hypertension and diabetes mellitus, due to important pathogenetic role of oxidative stress.https://cardiovascular.elpub.ru/jour/article/view/1097ace inhibitorcaptoprilzofenopril
collection DOAJ
language Russian
format Article
sources DOAJ
author D. V. Preobrazhensky
B. A. Sidorenko
S. A. S.A. Pataraya
A. V. Skorik
spellingShingle D. V. Preobrazhensky
B. A. Sidorenko
S. A. S.A. Pataraya
A. V. Skorik
Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
Кардиоваскулярная терапия и профилактика
ace inhibitor
captopril
zofenopril
author_facet D. V. Preobrazhensky
B. A. Sidorenko
S. A. S.A. Pataraya
A. V. Skorik
author_sort D. V. Preobrazhensky
title Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
title_short Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
title_full Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
title_fullStr Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
title_full_unstemmed Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
title_sort pleiotropic ace inhibitor effects: any benefits for sulfhydryl agents?
publisher «SILICEA-POLIGRAF» LLC
series Кардиоваскулярная терапия и профилактика
issn 1728-8800
2619-0125
publishDate 2008-02-01
description Clinical pharmacology of ACE inhibitors is described, comparing pharmacological effects of agents with or without sulfhydryl groups in their molecules. Sulfhydryl group-containing ACE inhibitors – captopril and especially zofenopril – are characterized by greater antioxidant properties and, potentially, stronger cardio- and vasoprotective action. Literature data confirm benefits of these sulfhydryl ACE inhibitors as first-line medications for treating acute myocardial infarction, other coronary heart disease forms, arterial hypertension and diabetes mellitus, due to important pathogenetic role of oxidative stress.
topic ace inhibitor
captopril
zofenopril
url https://cardiovascular.elpub.ru/jour/article/view/1097
work_keys_str_mv AT dvpreobrazhensky pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents
AT basidorenko pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents
AT sasapataraya pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents
AT avskorik pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents
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