Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?
Clinical pharmacology of ACE inhibitors is described, comparing pharmacological effects of agents with or without sulfhydryl groups in their molecules. Sulfhydryl group-containing ACE inhibitors – captopril and especially zofenopril – are characterized by greater antioxidant properties and, potentia...
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«SILICEA-POLIGRAF» LLC
2008-02-01
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Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1097 |
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doaj-6287b1f1cd99427b85e5e716224a4cec2021-07-28T13:50:46Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-02-0171116123809Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents?D. V. Preobrazhensky0B. A. Sidorenko1S. A. S.A. Pataraya2A. V. Skorik3I.M. Sechenov Moscow Medical Academy; Education and Research Medical Center, RF President’s AdministrationEducation and Research Medical Center, RF President’s AdministrationEducation and Research Medical Center, RF President’s AdministrationCentral Clinical Hospital, RF President’s Administration. MoscowClinical pharmacology of ACE inhibitors is described, comparing pharmacological effects of agents with or without sulfhydryl groups in their molecules. Sulfhydryl group-containing ACE inhibitors – captopril and especially zofenopril – are characterized by greater antioxidant properties and, potentially, stronger cardio- and vasoprotective action. Literature data confirm benefits of these sulfhydryl ACE inhibitors as first-line medications for treating acute myocardial infarction, other coronary heart disease forms, arterial hypertension and diabetes mellitus, due to important pathogenetic role of oxidative stress.https://cardiovascular.elpub.ru/jour/article/view/1097ace inhibitorcaptoprilzofenopril |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
D. V. Preobrazhensky B. A. Sidorenko S. A. S.A. Pataraya A. V. Skorik |
spellingShingle |
D. V. Preobrazhensky B. A. Sidorenko S. A. S.A. Pataraya A. V. Skorik Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents? Кардиоваскулярная терапия и профилактика ace inhibitor captopril zofenopril |
author_facet |
D. V. Preobrazhensky B. A. Sidorenko S. A. S.A. Pataraya A. V. Skorik |
author_sort |
D. V. Preobrazhensky |
title |
Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents? |
title_short |
Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents? |
title_full |
Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents? |
title_fullStr |
Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents? |
title_full_unstemmed |
Pleiotropic ACE inhibitor effects: any benefits for sulfhydryl agents? |
title_sort |
pleiotropic ace inhibitor effects: any benefits for sulfhydryl agents? |
publisher |
«SILICEA-POLIGRAF» LLC |
series |
Кардиоваскулярная терапия и профилактика |
issn |
1728-8800 2619-0125 |
publishDate |
2008-02-01 |
description |
Clinical pharmacology of ACE inhibitors is described, comparing pharmacological effects of agents with or without sulfhydryl groups in their molecules. Sulfhydryl group-containing ACE inhibitors – captopril and especially zofenopril – are characterized by greater antioxidant properties and, potentially, stronger cardio- and vasoprotective action. Literature data confirm benefits of these sulfhydryl ACE inhibitors as first-line medications for treating acute myocardial infarction, other coronary heart disease forms, arterial hypertension and diabetes mellitus, due to important pathogenetic role of oxidative stress. |
topic |
ace inhibitor captopril zofenopril |
url |
https://cardiovascular.elpub.ru/jour/article/view/1097 |
work_keys_str_mv |
AT dvpreobrazhensky pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents AT basidorenko pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents AT sasapataraya pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents AT avskorik pleiotropicaceinhibitoreffectsanybenefitsforsulfhydrylagents |
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1721271345676812288 |