The Role of STAT3 in Non-Small Cell Lung Cancer
Persistent phosphorylation of signal transducer and activator of transcription 3 (STAT3) has been demonstrated in 22%~65% of non-small cell lung cancers (NSCLC). STAT3 activation is mediated by receptor tyrosine kinases, such as epidermal growth factor receptor (EGFR) and MET, cytokine receptors, s...
Main Authors: | Daijiro Harada, Nagio Takigawa, Katsuyuki Kiura |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-03-01
|
Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/6/2/708 |
Similar Items
-
Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway
by: Charles J. Malemud
Published: (2010-05-01) -
STAT3: Versatile Functions in Non-Small Cell Lung Cancer
by: Julian Mohrherr, et al.
Published: (2020-04-01) -
Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism
by: Yuchen Nan, et al.
Published: (2017-12-01) -
Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms
by: Paula Montero, et al.
Published: (2021-06-01) -
Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages
by: Xin Zhang, et al.
Published: (2017-05-01)