Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery
Background & Objective: Monitoring the depth of anesthesia is very important to prevent undesirable events during surgery, such as intra operative awareness and overdosing. It is shown that anesthetic agents have direct effects on synaptic activity of brain neurons. So there is a great interest...
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Golestan University of Medical Sciences
2008-07-01
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Online Access: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-303&slc_lang=en&sid=1 |
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doaj-62a4b465e43d4ba1ba311d88de1f778d2020-11-24T21:43:10ZfasGolestan University of Medical Sciences مجله دانشگاه علوم پزشکی گرگان1562-47652008-40802008-07-011024449Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgeryAlireza Mehri Dehnavi (PhD)0Rasoul Amirfattahi (PhD)1Mojtaba Mansoori (PhD)2Behzad Ahmadi (MSc)3Ehsan Negahbani (MSc)4 Background & Objective: Monitoring the depth of anesthesia is very important to prevent undesirable events during surgery, such as intra operative awareness and overdosing. It is shown that anesthetic agents have direct effects on synaptic activity of brain neurons. So there is a great interest on electroencephalogram analysis as a depth of anesthesia estimator. Due to difficulties in visual explanation of EEG, automatic and computer based signal processing methods have been used to assess the depth of anesthesia. Investigating the relationship between conscious level of patients and electrical activity of brain neurons was the main aim of this study. Materials & Methods: In this study, EEG signals of six patients undergoing aortic valve replacement surgery have been acquired and recorded in a computer. After applying signal processing methods to these data, 3 different measures included temporal, spectral and bispectral parameters have been extracted. Mean values of mentioned parameters in different anesthetic regimens and levels have been analyzed by ANOVA in SPSS software. Results: Extracted temporal parameter is correlated with depth of anesthesia in deep anesthetic levels and spectral one is correlated with depth of anesthesia in moderate and light levels (P<0.05). Bispectral parameter is correlated with the depth of anesthesia only in ICU (P<0.05). Conclusion: Findings of this study confirm the relationship between consciousness and electrical activity of brain neurons and recommend the use of EEG processing techniques to monitor, control and estimate the depth of anesthesia in operating room and ICU ward.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-303&slc_lang=en&sid=1Depth of anesthesiaBrain wavesSignal processing |
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DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
Alireza Mehri Dehnavi (PhD) Rasoul Amirfattahi (PhD) Mojtaba Mansoori (PhD) Behzad Ahmadi (MSc) Ehsan Negahbani (MSc) |
spellingShingle |
Alireza Mehri Dehnavi (PhD) Rasoul Amirfattahi (PhD) Mojtaba Mansoori (PhD) Behzad Ahmadi (MSc) Ehsan Negahbani (MSc) Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery مجله دانشگاه علوم پزشکی گرگان Depth of anesthesia Brain waves Signal processing |
author_facet |
Alireza Mehri Dehnavi (PhD) Rasoul Amirfattahi (PhD) Mojtaba Mansoori (PhD) Behzad Ahmadi (MSc) Ehsan Negahbani (MSc) |
author_sort |
Alireza Mehri Dehnavi (PhD) |
title |
Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery |
title_short |
Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery |
title_full |
Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery |
title_fullStr |
Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery |
title_full_unstemmed |
Relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery |
title_sort |
relationship between consciousness and electrical activity of brain neurons in patients undergoing aortic valve replacement surgery |
publisher |
Golestan University of Medical Sciences |
series |
مجله دانشگاه علوم پزشکی گرگان |
issn |
1562-4765 2008-4080 |
publishDate |
2008-07-01 |
description |
Background & Objective: Monitoring the depth of anesthesia is very important to prevent undesirable events during surgery, such as intra operative awareness and overdosing. It is shown that anesthetic agents have direct effects on synaptic activity of brain neurons. So there is a great interest on electroencephalogram analysis as a depth of anesthesia estimator. Due to difficulties in visual explanation of EEG, automatic and computer based signal processing methods have been used to assess the depth of anesthesia. Investigating the relationship between conscious level of patients and electrical activity of brain neurons was the main aim of this study. Materials & Methods: In this study, EEG signals of six patients undergoing aortic valve replacement surgery have been acquired and recorded in a computer. After applying signal processing methods to these data, 3 different measures included temporal, spectral and bispectral parameters have been extracted. Mean values of mentioned parameters in different anesthetic regimens and levels have been analyzed by ANOVA in SPSS software. Results: Extracted temporal parameter is correlated with depth of anesthesia in deep anesthetic levels and spectral one is correlated with depth of anesthesia in moderate and light levels (P<0.05). Bispectral parameter is correlated with the depth of anesthesia only in ICU (P<0.05). Conclusion: Findings of this study confirm the relationship between consciousness and electrical activity of brain neurons and recommend the use of EEG processing techniques to monitor, control and estimate the depth of anesthesia in operating room and ICU ward. |
topic |
Depth of anesthesia Brain waves Signal processing |
url |
http://goums.ac.ir/journal/browse.php?a_code=A-10-1-303&slc_lang=en&sid=1 |
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