Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System
A system which allows magnetic resonance (MR) and ultrasound (US) image data to be acquired simultaneously has been developed. B-mode and Doppler US were performed inside the bore of a clinical 1.5 T MRI scanner using a clinical 1–4 MHz US transducer with an 8-metre cable. Susceptibility artefacts a...
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Online Access: | http://dx.doi.org/10.1155/2014/914347 |
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doaj-62d32e7d57e04e2daa3999b90cba16692020-11-24T23:44:22ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/914347914347Development of a Hybrid Magnetic Resonance and Ultrasound Imaging SystemVictoria Sherwood0John Civale1Ian Rivens2David J. Collins3Martin O. Leach4Gail R. ter Haar5Division of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKDivision of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKDivision of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKDepartment of Clinical Magnetic Resonance, CRUK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKDepartment of Clinical Magnetic Resonance, CRUK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKDivision of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKA system which allows magnetic resonance (MR) and ultrasound (US) image data to be acquired simultaneously has been developed. B-mode and Doppler US were performed inside the bore of a clinical 1.5 T MRI scanner using a clinical 1–4 MHz US transducer with an 8-metre cable. Susceptibility artefacts and RF noise were introduced into MR images by the US imaging system. RF noise was minimised by using aluminium foil to shield the transducer. A study of MR and B-mode US image signal-to-noise ratio (SNR) as a function of transducer-phantom separation was performed using a gel phantom. This revealed that a 4 cm separation between the phantom surface and the transducer was sufficient to minimise the effect of the susceptibility artefact in MR images. MR-US imaging was demonstrated in vivo with the aid of a 2 mm VeroWhite 3D-printed spherical target placed over the thigh muscle of a rat. The target allowed single-point registration of MR and US images in the axial plane to be performed. The system was subsequently demonstrated as a tool for the targeting and visualisation of high intensity focused ultrasound exposure in the rat thigh muscle.http://dx.doi.org/10.1155/2014/914347 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Victoria Sherwood John Civale Ian Rivens David J. Collins Martin O. Leach Gail R. ter Haar |
spellingShingle |
Victoria Sherwood John Civale Ian Rivens David J. Collins Martin O. Leach Gail R. ter Haar Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System BioMed Research International |
author_facet |
Victoria Sherwood John Civale Ian Rivens David J. Collins Martin O. Leach Gail R. ter Haar |
author_sort |
Victoria Sherwood |
title |
Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System |
title_short |
Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System |
title_full |
Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System |
title_fullStr |
Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System |
title_full_unstemmed |
Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System |
title_sort |
development of a hybrid magnetic resonance and ultrasound imaging system |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2014-01-01 |
description |
A system which allows magnetic resonance (MR) and ultrasound (US) image data to be acquired simultaneously has been developed. B-mode and Doppler US were performed inside the bore of a clinical 1.5 T MRI scanner using a clinical 1–4 MHz US transducer with an 8-metre cable. Susceptibility artefacts and RF noise were introduced into MR images by the US imaging system. RF noise was minimised by using aluminium foil to shield the transducer. A study of MR and B-mode US image signal-to-noise ratio (SNR) as a function of transducer-phantom separation was performed using a gel phantom. This revealed that a 4 cm separation between the phantom surface and the transducer was sufficient to minimise the effect of the susceptibility artefact in MR images. MR-US imaging was demonstrated in vivo with the aid of a 2 mm VeroWhite 3D-printed spherical target placed over the thigh muscle of a rat. The target allowed single-point registration of MR and US images in the axial plane to be performed. The system was subsequently demonstrated as a tool for the targeting and visualisation of high intensity focused ultrasound exposure in the rat thigh muscle. |
url |
http://dx.doi.org/10.1155/2014/914347 |
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