A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease

A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease

Dysregulation of several metabolite pathways, including branched-chain amino acids (BCAAs), are associated with Non-Alcoholic Fatty Liver Disease (NAFLD) and insulin resistance in adults, while studies in youth reported conflicting results. We explored whether, independently of obesity and insulin r...

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Bibliographic Details
Main Authors: Martina Goffredo, Nicola Santoro, Domenico Tricò, Cosimo Giannini, Ebe D’Adamo, Hongyu Zhao, Gang Peng, Xiaoqing Yu, Tukiet T. Lam, Bridget Pierpont, Sonia Caprio, Raimund I. Herzog
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Nutrients
Subjects:
metabolomics
youth
branched chain amino acids
insulin resistance
nonalcoholic fatty liver disease
obesity
Online Access:http://www.mdpi.com/2072-6643/9/7/642

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